Probing pathways by which rhynchophylline modifies sleep using spatial transcriptomics
Abstract Background Rhynchophylline (RHY) is an alkaloid component of Uncaria, which are plants extensively used in traditional Asian medicines.Uncaria treatments increase sleep time and quality in humans, and RHY induces sleep in rats.However, like many traditional natural treatments, the mechanisms of action of RHY and Uncaria remain evasive.More